Tri Wibawa, MD, PhD

tri

Qualification:

1988-1995: Medical Doctor

1996-1998: Research Student in Molecular Genetics at Kobe University School of Medicine, Japan (non degree)

1998-2002: PhD in Molecular Medicine at KobeUniversityGraduateSchool of Medicine, Japan.

Research experience and interest:

1996-2002: Mutation screening of the dystrophin gene in DMD and BMD patients.

1997-1998: Identification of novel transcript of the dystrophin gene.

2000-2002: Genetic susceptibility of Mycobacterium leprae infection.

2003-2004: Macrophages apoptosis induced by isoniazid resistant Mycobacterium  tuberculosis

2005-2007: Genetic susceptibility of dengue virus infection.

2007-2008: Molecular detection of dengue virus.  Molecular detection of M tuberculosis resistant to isoniazid.

2008-2009: Clinical trial of standardized herbal medicine to the dengue virus infected patients.

2009         : Dengue virus genome library construction.

2009-2010: Effect of cyclosporine A to the fluconazol resistant Candida albicans

2010-         : Genotyping and phenotyping of dengue virus to predict the severity and clinical manifestation of dengue virus infection.

2010-2011: Analysis of NS-1 gene of  dengue virus

2011         : Molecular characterization of pre membrane gene as a toll for dengue virus serotyping

2011        : Detection of wolbachia sp  in Ae. Albopictus.

2012-        : International Research Consortium on Dengue Risk Assessment, Management and Surveillance (research team member)

2012-        : Association of Polymorphisms of DC-SIGN (CD209) Carbohydrate Recognition Domain with Dengue Virus Infection.

2013-        : National Consortium on Dengue Vaccine Development

Publications:

Surono A, Takeshima Y, Wibawa T, Pramono ZA, Matsuo M

Six novel transcripts that remove a huge intron ranging from 250 to 800 kb are produced by alternative splicing of the 5′ region of the dystrophin gene in human skeletal muscle.
Biochemical and Biophysical Research Communications 1997 Oct 29;239(3):895-9.

Wibawa T, Takeshima Y, Surono A, Pramono ZAD, Matsuo M

A novel point mutation (G+5 to T) at a splice donor site of intron 66 of the dystrophin gene identified in DMD leads to complete skipping of exon 66, but no error in alternative splicing of downstream exons American Journal of Human Genetics, 1997; 61: 4 Suppl. A350

Wibawa T, Takeshima Y, Mitsuyoshi I, Wada H, Surono A, Nakamura H, Matsuo M.

Two Duchenne muscular dystrophy cases with severe mental retardation had the same complete skipping of exon 66 in dystrophin transcript due to two different point mutations of the dystrophin gene American Journal of Human Genetics, 1998; 63: 4 Suppl. A393

Surono A, Takeshima Y, Wibawa T, Ikezawa M, Nonaka I, Matsuo M.

Circular dystrophin RNAs consisting of exons that were skipped by alternative splicing.
Human Molecular Genetics 1999 Mar;8(3):493-500.

Wibawa T, Takeshima Y, Mitsuyoshi I, Wada H, Surono A, Nakamura H, Matsuo M.

Complete skipping of exon 66 due to novel mutations of the dystrophin gene was identified in two Japanese families of Duchenne muscular dystrophy with severe mental retardation. Brain and Development 2000 Mar;22(2):107-12.

Wibawa T, Soebono H, Matsuo M

Association of a missense mutation of the laminin alpha 2 gene with tuberculoid type of leprosy in Indonesian patients Tropical Medicine and International Health, 2002 , 7 (7) 631-636

Rachmawaty FJ, Wibawa T, Susatyo MHNE, Apoptosis and Phagocytosis Activity of Macrophages Infected y Mycobacterium tuberculosis Resistant and Sensitive Isoniazid Clinical Isolates Indonesian Journal of Biotechnology, 2006, 12 (2): 895-900

Wijayanti N, Wibawa T, Nirwati H, Haryanto A, Sutaryo, Rapid Detection and Molecular Typing of Dengue Virus Using Multiplex-Nested- RT-PCR Assay. Indonesian Journal of Biotechnology, 2006, 12 (2):

Rintiswati N, Wibawa T, 2008, Detection of Mutation on katG S315T and R463L among

Isoniazid Resistance  Mycobacteriun tuberculosis Clinical Isolates from Java, Proceeding of International Joint Symposium UGM-NAIST-USM.

Aisyah R, Wibawa T, Asmara W, Analisis Molekuler Gen Polymerase Basic 2 (PB2) Virus Avian Influenza H5N1 yang Diisolasi dari Unggas Asal Purworejo, Jawa Tengah dan Bantul, Yogyakarta, Biomedika 2010, 2(1), 6-16

Triyana SY, Wibawa T, Asmara W, Analisis Molekular Gen NS1 Virus Avian Influenza  H5N1 yang Diisolasi dari Unggas Asal Purworejo Jawa Tengah  dan Bantul Daerah Istimewa Yogyakarta, Biomedika 2010, 2(2), 79-88

Wibawa T, Surono A, Widodo I, 2011, Isolation of Viable Helicobacter pylori in the Tonsilar Tissues of Chronic Tonsillitis Patients. The Journal of Infection in Developing Countries, 5(7):561-564

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